The series starts with two brothers, Sam and Dean, whose mother died in a fire when they were kids, on the road trying to find their father, a ghost/demon hunter who went missing. While on the road, they started saving innocent people by battling ghosts, demons, vampires, and other creatures following a "Monster of the Week" theme.
After they found their father, it was revealed to them that the creature that killed their mother was a demon named Azazel, and they were told how to kill that creature. The boys later go hunting for Azazel, whom they end up killing in the second season. That's when the plot starts thickening up. Dean makes a deal with a demon to save Sam, and as part of the deal, he has only one year left on Earth before he is sent to Hell.
Initially, the series was more about the "Monster of the Week", but as the series progressed, the storyline expanded by including elements from different mythologies, and the show became more than just about monsters.
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