While having a demonic character with a shared name may be the most obvious connection between the two shows, best reference to is via its own use of the Antichrist in season 5. In season 5, episode 6, dubbed “I Believe the Children Are Our Future,” Sam and Dean Winchester are tasked with investigating rumors that involve fairy tales and urban legends coming to life.
Quite unexpectedly, the culprit ends up being a boy named Jesse who can warp the very fabric of reality, thanks to his status as an Antichrist.
While Jesse is not the literal son of Lucifer, but rather a half-human born from a mother possessed by a demon, Kripke has been open about basing the character on Adam from the original book. With the same book later providing the basis for , viewers of both shows would be able to see several parallels between the characters and how their abilities were manifested.
Moreover, both characters were able to exercise their own free will and avoid becoming the cause of a potential apocalypse.
With Gaiman already well aware of Kripke’s love of his work as an author, perhaps
will give him the opportunity to return the favor. With a whole host of angels waiting to be introduced, Gaiman may even look to introduce his own version of Castiel as a sneaky reciprocal nod to . Or, even better, Crowley and Aziraphale may potentially find themselves crossing paths with a pair of brothers named Sam and Dean.