Jean-Claude Van Damme shared his memories of working with Jennifer Aniston on the hit television show Friends. However, he clarified that despite her stunning looks, he did not have a crush on her because he was already in love with his wife, Gladys Portugues. In an interview with The New York Post while promoting his new Irish whiskey brand, Old Oak, Jean-Claude praised his wife as an amazing woman from New York.

He described her as a champion bodybuilder who achieved her muscular physique naturally, without the use of any special products or enhancements. Jean-Claude shared that he first saw Gladys on the cover of Muscle and Fitness and told his friend that he would marry her when he went to America. Jean-Claude and Gladys had a tumultuous relationship. They got married in 1987 but went through a period of separation before reconciling and remarrying in 1999.

Throughout their marriage, they have been blessed with three children. Overall, Jean-Claude Van Damme reminisced about his time working with Jennifer Aniston on Friends but emphasized his unwavering love and loyalty to his wife, Gladys Portugues.