Jensen Ackles, known for his role as Dean Winchester in Supernatural and The Winchesters, has spoken out about the cancellation of the spin-off show and expressed his gratitude to fans for their support. The CW Network, under Nexstar's management, cracked down on scripted content, resulting in The Winchesters being canceled after just one season. In a statement on Twitter, Ackles shared his disappointment regarding the news and thanked those who watched, followed, and supported the show.

He commended the efforts of everyone involved in bringing the series to life and expressed his pride in their collective achievements. Nevertheless, Ackles acknowledged that timing played a significant role, referring to the recent shift within the network and the ongoing WGA writers' strike. Ackles hinted that the strike may have contributed to the premature end of the show. The network also cited the need to make tough programming decisions as they reimagined the new CW. The cancellation of The Winchesters and Kung Fu was announced together, with the network expressing gratitude towards Warner Bros., the casts, and creative teams for their hard work, creativity, and dedication. Creator Robbie Thompson, who had envisioned expanding the Supernatural universe with The Winchesters, expressed his disappointment at the news. He believed that the show had the potential to explore numerous stories and emphasized the resilience of the characters in the face of death. Prior to his Twitter statement, Ackles had attempted to save The Winchesters by setting up a petition, although it ultimately proved unsuccessful. Ackles' tweet serves as a final farewell to the show, expressing hope for a future reunion somewhere down the road.